Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity

Natural killer (NK) cells are cytotoxic innate lymphoid cells (ILCs) that mediate antiviral and antitumor responses and require the transcriptional regulator Eomesodermin (Eomes) for early development. However, the role of Eomes and its molecular program in mature NK cell biology is unclear. To addr...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Wagner, Julia A., Wong, Pamela, Schappe, Timothy, Berrien-Elliott, Melissa M., Cubitt, Celia, Jaeger, Natalia, Lee, Madeline, Keppel, Cassie R., Marin, Nancy D., Foltz, Jennifer A., Marsala, Lynne, Neal, Carly C., Sullivan, Ryan P., Schneider, Stephanie E., Keppel, Molly P., Saucier, Nermina, Cooper, Megan A., Fehniger, Todd A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Author(s). 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265846/
https://ncbi.nlm.nih.gov/pubmed/32492428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107720
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