Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity

Natural killer (NK) cells are cytotoxic innate lymphoid cells (ILCs) that mediate antiviral and antitumor responses and require the transcriptional regulator Eomesodermin (Eomes) for early development. However, the role of Eomes and its molecular program in mature NK cell biology is unclear. To addr...

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Publicado no:Cell Rep
Main Authors: Wagner, Julia A., Wong, Pamela, Schappe, Timothy, Berrien-Elliott, Melissa M., Cubitt, Celia, Jaeger, Natalia, Lee, Madeline, Keppel, Cassie R., Marin, Nancy D., Foltz, Jennifer A., Marsala, Lynne, Neal, Carly C., Sullivan, Ryan P., Schneider, Stephanie E., Keppel, Molly P., Saucier, Nermina, Cooper, Megan A., Fehniger, Todd A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Author(s). 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265846/
https://ncbi.nlm.nih.gov/pubmed/32492428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107720
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