Ładuje się......
IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses
T cell receptor (TCR) activation is modulated by mechanisms such as TCR endocytosis, which is thought to terminate TCR signalling. Here we show that, upon internalization, TCR continues to signal from a set of specialized endosomes that are crucial for T cell functions. Mechanistically, TCR ligation...
Zapisane w:
| Wydane w: | Nat Commun |
|---|---|
| Główni autorzy: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2020
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7265453/ https://ncbi.nlm.nih.gov/pubmed/32487999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16471-7 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|