The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells

Insulin regulated aminopeptidase (IRAP) is a type II transmembrane protein with broad tissue distribution initially identified as a major component of Glut4 storage vesicles (GSV) in adipocytes. Despite its almost ubiquitous expression, IRAP had been extensively studied mainly in insulin responsive...

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Publicat a:Front Mol Biosci
Autors principals: Descamps, Delphyne, Evnouchidou, Irini, Caillens, Vivien, Drajac, Carole, Riffault, Sabine, van Endert, Peter, Saveanu, Loredana
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Molecular Biosciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606930/
https://ncbi.nlm.nih.gov/pubmed/33195428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.583556
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