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Prolonged mitosis results in structurally aberrant and over-elongated centrioles

Centrioles are precisely built microtubule-based structures that assemble centrosomes and cilia. Aberrations in centriole structure are common in tumors, yet how these aberrations arise is unknown. Analysis of centriole structure is difficult because it requires demanding electron microscopy. Here w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Kong, Dong, Sahabandu, Natalie, Sullenberger, Catherine, Vásquez-Limeta, Alejandra, Luvsanjav, Delgermaa, Lukasik, Kimberly, Loncarek, Jadranka
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265320/
https://ncbi.nlm.nih.gov/pubmed/32271878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201910019
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