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Prolonged mitosis results in structurally aberrant and over-elongated centrioles

Centrioles are precisely built microtubule-based structures that assemble centrosomes and cilia. Aberrations in centriole structure are common in tumors, yet how these aberrations arise is unknown. Analysis of centriole structure is difficult because it requires demanding electron microscopy. Here w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Kong, Dong, Sahabandu, Natalie, Sullenberger, Catherine, Vásquez-Limeta, Alejandra, Luvsanjav, Delgermaa, Lukasik, Kimberly, Loncarek, Jadranka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265320/
https://ncbi.nlm.nih.gov/pubmed/32271878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201910019
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