Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B

Two mitotic cyclin types, cyclin A and B, exist in higher eukaryotes, but their specialised functions in mitosis are incompletely understood. Using degron tags for rapid inducible protein removal, we analyse how acute depletion of these proteins affects mitosis. Loss of cyclin A in G2‐phase prevents...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Hégarat, Nadia, Crncec, Adrijana, Suarez Peredo Rodriguez, Maria F, Echegaray Iturra, Fabio, Gu, Yan, Busby, Oliver, Lang, Paul F, Barr, Alexis R, Bakal, Chris, Kanemaki, Masato T, Lamond, Angus I, Novak, Bela, Ly, Tony, Hochegger, Helfrid
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265243/
https://ncbi.nlm.nih.gov/pubmed/32350921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104419
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