Glutathione restricts serine metabolism to preserve regulatory T cell function

Regulatory T cells (Tregs) maintain immune homeostasis and prevent autoimmunity. Serine stimulates glutathione (GSH) synthesis and feeds into the one-carbon metabolic network (1CMet) essential for effector T cell (Teff) responses. However, serine’s functions, linkage to GSH, and role in stress respo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Metab
मुख्य लेखकों: Kurniawan, Henry, Franchina, Davide G., Guerra, Luana, Bonetti, Lynn, Soriano-Baguet, Leticia, Grusdat, Melanie, Schlicker, Lisa, Hunewald, Oliver, Dostert, Catherine, Merz, Myriam P., Binsfeld, Carole, Duncan, Gordon S., Farinelle, Sophie, Nonnenmacher, Yannic, Haight, Jillian, Gupta, Dennis Das, Ewen, Anouk, Taskesen, Rabia, Halder, Rashi, Chen, Ying, Jäger, Christian, Ollert, Markus, Wilmes, Paul, Vasiliou, Vasilis, Harris, Isaac S., Knobbe-Thomsen, Christiane B., Turner, Jonathan D., Mak, Tak W., Lohoff, Michael, Meiser, Johannes, Hiller, Karsten, Brenner, Dirk
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265172/
https://ncbi.nlm.nih.gov/pubmed/32213345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.03.004
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