Glutathione restricts serine metabolism to preserve regulatory T cell function

Regulatory T cells (Tregs) maintain immune homeostasis and prevent autoimmunity. Serine stimulates glutathione (GSH) synthesis and feeds into the one-carbon metabolic network (1CMet) essential for effector T cell (Teff) responses. However, serine’s functions, linkage to GSH, and role in stress respo...

詳細記述

保存先:
書誌詳細
出版年:Cell Metab
主要な著者: Kurniawan, Henry, Franchina, Davide G., Guerra, Luana, Bonetti, Lynn, Soriano-Baguet, Leticia, Grusdat, Melanie, Schlicker, Lisa, Hunewald, Oliver, Dostert, Catherine, Merz, Myriam P., Binsfeld, Carole, Duncan, Gordon S., Farinelle, Sophie, Nonnenmacher, Yannic, Haight, Jillian, Gupta, Dennis Das, Ewen, Anouk, Taskesen, Rabia, Halder, Rashi, Chen, Ying, Jäger, Christian, Ollert, Markus, Wilmes, Paul, Vasiliou, Vasilis, Harris, Isaac S., Knobbe-Thomsen, Christiane B., Turner, Jonathan D., Mak, Tak W., Lohoff, Michael, Meiser, Johannes, Hiller, Karsten, Brenner, Dirk
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265172/
https://ncbi.nlm.nih.gov/pubmed/32213345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.03.004
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料