Intercellular Sodium Regulates Repolarization in Cardiac Tissue with Sodium Channel Gain of Function

In cardiac myocytes, action potentials are initiated by an influx of sodium (Na(+)) ions via voltage-gated Na(+) channels. Na(+) channel gain of function (GOF), arising in both inherited conditions associated with mutation in the gene encoding the Na(+) channel and acquired conditions associated wit...

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Udgivet i:Biophys J
Main Authors: Nowak, Madison B., Greer-Short, Amara, Wan, Xiaoping, Wu, Xiaobo, Deschênes, Isabelle, Weinberg, Seth H., Poelzing, Steven
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264809/
https://ncbi.nlm.nih.gov/pubmed/32402243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.04.014
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