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Mechanisms underlying age-associated manifestation of cardiac sodium channel gain-of-function
Cardiac action potentials are initiated by sodium ion (Na(+)) influx through voltage-gated Na(+) channels. Na(+) channel gain-of-function (GOF) can arise in inherited conditions due to mutations in the gene encoding the cardiac Na(+) channel, such as Long QT syndrome type 3 (LQT3). LQT3 can be a “co...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8026540/ https://ncbi.nlm.nih.gov/pubmed/33373643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.12.008 |
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