Disrupting nNOS–PSD95 Interaction Improves Neurological and Cognitive Recoveries after Traumatic Brain Injury

Excessive activation of N-methyl-D-aspartate receptors (NMDARs) and the resulting neuronal nitric oxide synthase (nNOS) activation plays a crucial role in the pathogenesis of traumatic brain injury (TBI). However, directly inhibiting NMDARs or nNOS produces adverse side effects because they play key...

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Pubblicato in:Cereb Cortex
Autori principali: Qu, Wenrui, Liu, Nai-Kui, Wu, Xiangbing, Wang, Ying, Xia, Yongzhi, Sun, Yan, Lai, Yvonne, Li, Rui, Shekhar, Anantha, Xu, Xiao-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264644/
https://ncbi.nlm.nih.gov/pubmed/31989159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhaa002
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