Disruption of nNOS-PSD95 protein–protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents

BACKGROUND AND PURPOSE: Post-synaptic density protein 95 (PSD95) contains three PSD95/Dosophilia disc large/ZO-1 homology domains and links neuronal nitric oxide synthase (nNOS) with the N-methyl-D-aspartic acid (NMDA) receptor. This report assesses the effects of disruption of the protein–protein i...

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Autors principals: Florio, SK, Loh, C, Huang, SM, Iwamaye, AE, Kitto, KF, Fowler, KW, Treiberg, JA, Hayflick, JS, Walker, JM, Fairbanks, CA, Lai, Y
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2009
Matèries:
Research Papers with Commentaries
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757689/
https://ncbi.nlm.nih.gov/pubmed/19732061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00300.x
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