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Tau induces PSD95-nNOS uncoupling and neurovascular dysfunction independent of neurodegeneration
Cerebrovascular abnormalities have emerged as a preclinical manifestation of Alzheimer’s disease and frontotemporal dementia, diseases characterized by accumulation of hyperphosphorylated forms of the microtubule associated protein tau. However, it is unclear if tau contributes to these neurovascula...
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| Veröffentlicht in: | Nat Neurosci |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7896353/ https://ncbi.nlm.nih.gov/pubmed/32778793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0686-7 |
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