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CYP2C19 polymorphisms and outcomes of Escitalopram treatment in Brazilians with major depression

Escitalopram (ESC), a selective serotonin reuptake inhibitor indicated for the treatment of depression and anxiety disorders, is primarily metabolized by cytochrome P450 (CYP) 2C19, which is a highly polymorphic enzyme known to cause inter-individual differences in pharmacokinetics. We hypothesized...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Bernini de Brito, Rodrigo, Ghedini, Paulo César
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264488/
https://ncbi.nlm.nih.gov/pubmed/32509985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e04015
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