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ABCB1 polymorphism predicts escitalopram dose needed for remission in major depression
The ATP-binding cassette family of transporter proteins, subfamily B (MDR/TAP), member 1 (ABCB1) (P-glycoprotein) transporter is a key component of the blood–brain barrier. Many antidepressants are subject to ABCB1 efflux. Functional polymorphisms of ABCB1 may influence central nervous system bioava...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565756/ https://ncbi.nlm.nih.gov/pubmed/23188198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.115 |
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