Engineered Circular RNA Sponges Act as miRNA Inhibitors to Attenuate Pressure Overload-Induced Cardiac Hypertrophy

Circular RNAs (circRNAs) sequester microRNAs (miRNAs) and repress their endogenous activity. We hypothesized that artificial circRNA sponges (circmiRs) can be constructed to target miRNAs therapeutically, with a low dosage requirement and extended half-lives compared to current alternatives. This co...

全面介紹

Na minha lista:
書目詳細資料
發表在:Mol Ther
Main Authors: Lavenniah, Annadoray, Luu, Tuan Danh Anh, Li, Yiqing Peter, Lim, Tingsen Benson, Jiang, Jianming, Ackers-Johnson, Matthew, Foo, Roger S.-Y.
格式: Artigo
語言:Inglês
出版: American Society of Gene & Cell Therapy 2020
主題:
Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264434/
https://ncbi.nlm.nih.gov/pubmed/32304667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.04.006
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍