Circular RNAs: Promising Molecular Biomarkers of Human Aging-Related Diseases via Functioning as an miRNA Sponge

Circular RNAs (circRNAs) are a new class of noncoding single-stranded RNAs that differ from linear microRNAs (miRNAs), since they form covalently closed loop structures without free 3′ poly(A) tails or 5′ caps. circRNAs are the competitive endogenous RNAs (ceRNAs) by binding to miRNA through miRNA r...

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Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Ren, Shuyue, Lin, Peirong, Wang, Jingrong, Yu, Haoying, Lv, Tingting, Sun, Lan, Du, Guanhua
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326721/
https://ncbi.nlm.nih.gov/pubmed/32637451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.05.027
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