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Effects of Glucose Deprivation on ATP and Proteoglycan Production of Intervertebral Disc Cells under Hypoxia

As the most common cause of low back pain, the cascade of intervertebral disc (IVD) degeneration is initiated by the disappearance of notochordal cells and progressive loss of proteoglycan (PG). Limited nutrient supply in the avascular disc environment restricts the production of ATP which is an ess...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yin, Xue, Motorwala, Aarif, Vesvoranan, Oraya, Levene, Howard B., Gu, Weiyong, Huang, Chun-Yuh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264337/
https://ncbi.nlm.nih.gov/pubmed/32483367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65691-w
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