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Effects of Glucose Deprivation on ATP and Proteoglycan Production of Intervertebral Disc Cells under Hypoxia

As the most common cause of low back pain, the cascade of intervertebral disc (IVD) degeneration is initiated by the disappearance of notochordal cells and progressive loss of proteoglycan (PG). Limited nutrient supply in the avascular disc environment restricts the production of ATP which is an ess...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Yin, Xue, Motorwala, Aarif, Vesvoranan, Oraya, Levene, Howard B., Gu, Weiyong, Huang, Chun-Yuh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264337/
https://ncbi.nlm.nih.gov/pubmed/32483367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65691-w
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