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Effects of Glucose Deprivation on ATP and Proteoglycan Production of Intervertebral Disc Cells under Hypoxia

As the most common cause of low back pain, the cascade of intervertebral disc (IVD) degeneration is initiated by the disappearance of notochordal cells and progressive loss of proteoglycan (PG). Limited nutrient supply in the avascular disc environment restricts the production of ATP which is an ess...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Yin, Xue, Motorwala, Aarif, Vesvoranan, Oraya, Levene, Howard B., Gu, Weiyong, Huang, Chun-Yuh
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264337/
https://ncbi.nlm.nih.gov/pubmed/32483367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65691-w
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