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Signaling from T cell receptors (TCRs) and chimeric antigen receptors (CARs) on T cells

T cells react to foreign or self-antigens through T cell receptor (TCR) signaling. Several decades of research have delineated the mechanism of TCR signal transduction and its impact on T cell performance. This knowledge provides the foundation for chimeric antigen receptor T cell (CAR-T cell) techn...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Wu, Ling, Wei, Qianru, Brzostek, Joanna, Gascoigne, Nicholas R. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264185/
https://ncbi.nlm.nih.gov/pubmed/32451454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-0470-3
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