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Overexpression of FAM46A, a Non-canonical Poly(A) Polymerase, Promotes Hemin-Induced Hemoglobinization in K562 Cells

FAM46A belongs to the FAM46 subfamily of the nucleotidyltransferase-fold superfamily and is predicted to be a non-canonical poly(A) polymerase. FAM46A has been linked to several human disorders including retinitis pigmentosa, bone abnormality, cancer, and obesity. However, its molecular and function...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Lin, Hsi-Hsien, Lo, Yu-Ling, Wang, Wen-Chih, Huang, Kuan-Yeh, I, Kuan-Yu, Chang, Gin-Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264091/
https://ncbi.nlm.nih.gov/pubmed/32528962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00414
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