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Xenobiotic Nuclear Receptor Signaling Determines Molecular Pathogenesis of Progressive Familial Intrahepatic Cholestasis

Progressive familial intrahepatic cholestasis (PFIC) is a genetically heterogeneous disorder of bile flow disruption due to abnormal canalicular transport or impaired bile acid (BA) metabolism, causing excess BA accumulation and liver failure. We previously reported an intrahepatic cholestasis mouse...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Kim, Kang Ho, Choi, Jong Min, Li, Feng, Arizpe, Armando, Wooton-Kee, Clavia Ruth, Anakk, Sayeepriyadarshini, Jung, Sung Yun, Finegold, Milton J, Moore, David D
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263843/
https://ncbi.nlm.nih.gov/pubmed/29718219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00110
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