Xenobiotic Nuclear Receptor Signaling Determines Molecular Pathogenesis of Progressive Familial Intrahepatic Cholestasis

Progressive familial intrahepatic cholestasis (PFIC) is a genetically heterogeneous disorder of bile flow disruption due to abnormal canalicular transport or impaired bile acid (BA) metabolism, causing excess BA accumulation and liver failure. We previously reported an intrahepatic cholestasis mouse...

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Publicado en:Endocrinology
Autores principales: Kim, Kang Ho, Choi, Jong Min, Li, Feng, Arizpe, Armando, Wooton-Kee, Clavia Ruth, Anakk, Sayeepriyadarshini, Jung, Sung Yun, Finegold, Milton J, Moore, David D
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2018
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263843/
https://ncbi.nlm.nih.gov/pubmed/29718219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00110
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