Constitutive Androstane Receptor Differentially Regulates Bile Acid Homeostasis in Mouse Models of Intrahepatic Cholestasis

Bile acid (BA) homeostasis is tightly regulated by multiple transcription factors, including farnesoid X receptor (FXR) and small heterodimer partner (SHP). We previously reported that loss of the FXR/SHP axis causes severe intrahepatic cholestasis, similar to human progressive familial intrahepatic...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Kim, Kang Ho, Choi, Jong Min, Li, Feng, Dong, Bingning, Wooton‐Kee, Clavia Ruth, Arizpe, Armando, Anakk, Sayeepriyadarshini, Jung, Sung Yun, Hartig, Sean M., Moore, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312660/
https://ncbi.nlm.nih.gov/pubmed/30620001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1274
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