Intragenic repeat expansion in the cell wall protein gene HPF1 controls yeast chronological aging

Aging varies among individuals due to both genetics and environment, but the underlying molecular mechanisms remain largely unknown. Using a highly recombined Saccharomyces cerevisiae population, we found 30 distinct quantitative trait loci (QTLs) that control chronological life span (CLS) in calori...

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Vydáno v:Genome Res
Hlavní autoři: Barré, Benjamin P., Hallin, Johan, Yue, Jia-Xing, Persson, Karl, Mikhalev, Ekaterina, Irizar, Agurtzane, Holt, Sylvester, Thompson, Dawn, Molin, Mikael, Warringer, Jonas, Liti, Gianni
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263189/
https://ncbi.nlm.nih.gov/pubmed/32277013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.253351.119
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