Intragenic repeat expansion in the cell wall protein gene HPF1 controls yeast chronological aging

Aging varies among individuals due to both genetics and environment, but the underlying molecular mechanisms remain largely unknown. Using a highly recombined Saccharomyces cerevisiae population, we found 30 distinct quantitative trait loci (QTLs) that control chronological life span (CLS) in calori...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Barré, Benjamin P., Hallin, Johan, Yue, Jia-Xing, Persson, Karl, Mikhalev, Ekaterina, Irizar, Agurtzane, Holt, Sylvester, Thompson, Dawn, Molin, Mikael, Warringer, Jonas, Liti, Gianni
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263189/
https://ncbi.nlm.nih.gov/pubmed/32277013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.253351.119
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