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Global fitness landscapes of the Shine-Dalgarno sequence
Shine-Dalgarno sequences (SD) in prokaryotic mRNA facilitate protein translation by pairing with rRNA in ribosomes. Although conventionally defined as AG-rich motifs, recent genomic surveys reveal great sequence diversity, questioning how SD functions. Here, we determined the molecular fitness (i.e....
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| Publicado no: | Genome Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7263185/ https://ncbi.nlm.nih.gov/pubmed/32424071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.260182.119 |
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