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Molecular structures and mechanisms of DNA break processing in mouse meiosis
Exonucleolytic resection, critical to repair double-strand breaks (DSBs) by recombination, is not well understood, particularly in mammalian meiosis. Here, we define structures of resected DSBs in mouse spermatocytes genome-wide at nucleotide resolution. Resection tracts averaged 1100 nt, but with s...
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| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7263140/ https://ncbi.nlm.nih.gov/pubmed/32354835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.336032.119 |
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