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Structural Insights into the Regulation of Ca(2+)/Calmodulin-Dependent Protein Kinase II (CaMKII)

Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is a highly conserved serine/threonine kinase that is ubiquitously expressed throughout the human body. Specialized isoforms of CaMKII play key roles in neuronal and cardiac signaling. The distinctive holoenzyme architecture of CaMKII, with 12–1...

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Detalles Bibliográficos
Publicado en:Cold Spring Harb Perspect Biol
Main Authors: Bhattacharyya, Moitrayee, Karandur, Deepti, Kuriyan, John
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263085/
https://ncbi.nlm.nih.gov/pubmed/31653643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a035147
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