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Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums

Changes in synaptic strength that underlie memory formation in the CNS are initiated by pulses of Ca(2+) flowing through NMDA-type glutamate receptors into postsynaptic spines. Differences in the duration and size of the pulses determine whether a synapse is potentiated or depressed after repetitive...

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Autori principali: Shifman, Julia M., Choi, Mee H., Mihalas, Stefan, Mayo, Stephen L., Kennedy, Mary B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599897/
https://ncbi.nlm.nih.gov/pubmed/16966599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606433103
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