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Swimming induced paralysis is a valuable behavioral assay to assess dopamine signaling in Caenorhabditis elegans.
The swimming assay described in this protocol is a valid tool to identify proteins regulating the dopaminergic synapses. Similarly to mammals, dopamine (DA) controls several functions in C. elegans including learning and motor activity. Conditions that stimulate DA release, e.g. amphetamine (AMPH) t...
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| Pubblicato in: | J Vis Exp |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7263014/ https://ncbi.nlm.nih.gov/pubmed/31009010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59243 |
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