Silencing of Syntaxin 1A in the Dopaminergic Neurons Decreases the Activity of the Dopamine Transporter and Prevents Amphetamine-Induced Behaviors in C. elegans

The dopamine transporter (DAT) is a cell membrane protein whose main function is to reuptake the dopamine (DA) released in the synaptic cleft back into the dopaminergic neurons. Previous studies suggested that the activity of DAT is regulated by allosteric proteins such as Syntaxin-1A and is altered...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Lanzo, Ambra, Safratowich, Bryan D., Kudumala, Sirisha R., Gallotta, Ivan, Zampi, Giuseppina, Di Schiavi, Elia, Carvelli, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972276/
https://ncbi.nlm.nih.gov/pubmed/29872404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00576
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