Forward Genetic Analysis to Identify Determinants of Dopamine Signaling in Caenorhabditis elegans Using Swimming-Induced Paralysis

Disrupted dopamine (DA) signaling is believed to contribute to the core features of multiple neuropsychiatric and neurodegenerative disorders. Essential features of DA neurotransmission are conserved in the nematode Caenorhabditis elegans, providing us with an opportunity to implement forward geneti...

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Detalhes bibliográficos
Main Authors: Hardaway, J. Andrew, Hardie, Shannon L., Whitaker, Sarah M., Baas, Sarah R., Zhang, Bing, Bermingham, Daniel P., Lichtenstein, Ariana J., Blakely, Randy D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
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Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411251/
https://ncbi.nlm.nih.gov/pubmed/22908044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.003533
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