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“LRRK2: Autophagy and Lysosomal Activity”

It has been 15 years since the Leucine-rich repeat kinase 2 (LRRK2) gene was identified as the most common genetic cause for Parkinson’s disease (PD). The two most common mutations are the LRRK2-G2019S, located in the kinase domain, and the LRRK2-R1441C, located in the ROC-COR domain. While the LRRK...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Neurosci
Main Authors: Madureira, Marta, Connor-Robson, Natalie, Wade-Martins, Richard
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262160/
https://ncbi.nlm.nih.gov/pubmed/32523507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00498
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