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Defactinib attenuates osteoarthritis by inhibiting positive feedback loop between H-type vessels and MSCs in subchondral bone
BACKGROUND: Abnormal bone formation in subchondral bone resulting from uncoupled bone remodeling is considered a central feature in osteoarthritis (OA) pathogenesis. H-type vessels can couple angiogenesis and osteogenesis. We previously revealed that elevated H-type vessels in subchondral bone were...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Orthop Translat |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Chinese Speaking Orthopaedic Society
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7261948/ https://ncbi.nlm.nih.gov/pubmed/32518750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jot.2020.04.008 |
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