Tumor Necrosis Factor Alpha Regulates Skeletal Myogenesis by Inhibiting SP1 Interaction with cis-Acting Regulatory Elements within the Fbxl2 Gene Promoter

FBXL2 is an important ubiquitin E3 ligase component that modulates inflammatory signaling and cell cycle progression, but its molecular regulation is largely unknown. Here, we show that tumor necrosis factor alpha (TNF-α), a critical cytokine linked to the inflammatory response during skeletal muscl...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: O’Brien, Michael E., Londino, James, McGinnis, Marcus, Weathington, Nathaniel, Adair, Jessica, Suber, Tomeka, Kagan, Valerian, Chen, Kong, Zou, Chunbin, Chen, Bill, Bon, Jessica, Mallampalli, Rama K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261720/
https://ncbi.nlm.nih.gov/pubmed/32205409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00040-20
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