Cargando...
The internal region of CtIP negatively regulates DNA end resection
DNA double-strand breaks are repaired by end-joining or homologous recombination. A key-committing step of recombination is DNA end resection. In resection, phosphorylated CtIP first promotes the endonuclease of MRE11–RAD50–NBS1 (MRN). Subsequently, CtIP also stimulates the WRN/BLM–DNA2 pathway, coo...
Guardado en:
| Publicado en: | Nucleic Acids Res |
|---|---|
| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2020
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7261161/ https://ncbi.nlm.nih.gov/pubmed/32347940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa273 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|