Biased signaling by endogenous opioid peptides

Opioids, such as morphine and fentanyl, are widely used for the treatment of severe pain; however, prolonged treatment with these drugs leads to the development of tolerance and can lead to opioid use disorder. The “Opioid Epidemic” has generated a drive for a deeper understanding of the fundamental...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gomes, Ivone, Sierra, Salvador, Lueptow, Lindsay, Gupta, Achla, Gouty, Shawn, Margolis, Elyssa B., Cox, Brian M., Devi, Lakshmi A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261131/
https://ncbi.nlm.nih.gov/pubmed/32393639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000712117
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