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Compartment-specific opioid receptor signaling is selectively modulated by different dynorphin peptides

Many signal transduction systems have an apparent redundancy built into them, where multiple physiological agonists activate the same receptors. Whether this is true redundancy, or whether this provides an as-yet unrecognized specificity in downstream signaling, is not well understood. We address th...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Kunselman, Jennifer M, Gupta, Achla, Gomes, Ivone, Devi, Lakshmi A, Puthenveedu, Manojkumar A
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112862/
https://ncbi.nlm.nih.gov/pubmed/33908346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60270
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