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Compartment-specific opioid receptor signaling is selectively modulated by different dynorphin peptides

Many signal transduction systems have an apparent redundancy built into them, where multiple physiological agonists activate the same receptors. Whether this is true redundancy, or whether this provides an as-yet unrecognized specificity in downstream signaling, is not well understood. We address th...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kunselman, Jennifer M, Gupta, Achla, Gomes, Ivone, Devi, Lakshmi A, Puthenveedu, Manojkumar A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112862/
https://ncbi.nlm.nih.gov/pubmed/33908346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60270
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