Drug screening identifies gemcitabine inhibiting rotavirus through alteration of pyrimidine nucleotide synthesis pathway

Although rotavirus infection is usually acute and self-limiting, it can cause chronic infection with severe diseases in immunocompromised patients, including organ transplantation recipients and cancer patients irrespective of pediatric or adult patients. Since no approved medication against rotavir...

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Pubblicato in:Antiviral Res
Autori principali: Chen, Sunrui, Wang, Yining, Li, Pengfei, Yin, Yuebang, Bijvelds, Marcel J., de Jonge, Hugo R., Peppelenbosch, Maikel P., Kainov, Denis E., Pan, Qiuwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Author(s). Published by Elsevier B.V. 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261112/
https://ncbi.nlm.nih.gov/pubmed/32485209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104823
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