6-Thioguanine inhibits rotavirus replication through suppression of Rac1 GDP/GTP cycling

Rotavirus infection has emerged as an important cause of complications in organ transplantation recipients and might play a role in the pathogenesis of inflammatory bowel disease (IBD). 6-Thioguanine (6-TG) has been widely used as an immunosuppressive drug for organ recipients and treatment of IBD i...

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Veröffentlicht in:Antiviral Res
Hauptverfasser: Yin, Yuebang, Chen, Sunrui, Hakim, Mohamad S., Wang, Wenshi, Xu, Lei, Dang, Wen, Qu, Changbo, Verhaar, Auke P., Su, Junhong, Fuhler, Gwenny M., Peppelenbosch, Maikel P., Pan, Qiuwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Authors. Published by Elsevier B.V. 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113846/
https://ncbi.nlm.nih.gov/pubmed/29920300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.06.011
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