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Basal interferon signaling and therapeutic use of interferons in controlling rotavirus infection in human intestinal cells and organoids

Rotavirus (RV) primarily infects enterocytes and results in severe diarrhea, particularly in children. It is known that the host immune responses determine the outcome of viral infections. Following infections, interferons (IFNs) are produced as the first and the main anti-viral cytokines to combat...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Hakim, Mohamad S., Chen, Sunrui, Ding, Shihao, Yin, Yuebang, Ikram, Aqsa, Ma, Xiao-xia, Wang, Wenshi, Peppelenbosch, Maikel P., Pan, Qiuwei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974418/
https://ncbi.nlm.nih.gov/pubmed/29844362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26784-9
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