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Paracrine regulation and improvement of β-cell function by thioredoxin
The failure of insulin-producing β-cells is the underlying cause of hyperglycemia in diabetes mellitus. β-cell decay has been linked to hypoxia, chronic inflammation, and oxidative stress. Thioredoxin (Trx) proteins are major actors in redox signaling and essential for signal transduction and the ce...
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| 出版年: | Redox Biol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7260591/ https://ncbi.nlm.nih.gov/pubmed/32473461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101570 |
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