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The specificity of thioredoxins and glutaredoxins is determined by electrostatic and geometric complementarity

Thiol–disulfide oxidoreductases from the thioredoxin (Trx) family of proteins have a broad range of well documented functions and possess distinct substrate specificities. The mechanisms and characteristics that control these specificities are key to the understanding of both the reduction of cataly...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Berndt, Carsten, Schwenn, Jens-Dirk, Lillig, Christopher Horst
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947528/
https://ncbi.nlm.nih.gov/pubmed/29861944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01501d
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