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Characterization of human glutaredoxin 2 as iron–sulfur protein: A possible role as redox sensor
Human mitochondrial glutaredoxin 2 (Grx2) is a glutathione-dependent oxidoreductase (active site: Cys-Ser-Tyr-Cys) that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Here, we have characterized Grx2 as an iron–sulfur center-containing...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1149418/ https://ncbi.nlm.nih.gov/pubmed/15917333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500735102 |
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