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Paracrine regulation and improvement of β-cell function by thioredoxin

The failure of insulin-producing β-cells is the underlying cause of hyperglycemia in diabetes mellitus. β-cell decay has been linked to hypoxia, chronic inflammation, and oxidative stress. Thioredoxin (Trx) proteins are major actors in redox signaling and essential for signal transduction and the ce...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Hanschmann, Eva-Maria, Petry, Sebastian Friedrich, Eitner, Susanne, Maresch, Constanze Christin, Lingwal, Neelam, Lillig, Christopher Horst, Linn, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260591/
https://ncbi.nlm.nih.gov/pubmed/32473461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101570
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