Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2

The ongoing global pandemic of coronavirus disease 2019 (COVID-19) has caused a huge number of human deaths. Currently, there are no specific drugs or vaccines available for this virus (SARS-CoV-2). The viral polymerase is a promising antiviral target. Here, we describe the near-atomic-resolution st...

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Vydáno v:Cell Rep
Hlavní autoři: Peng, Qi, Peng, Ruchao, Yuan, Bin, Zhao, Jingru, Wang, Min, Wang, Xixi, Wang, Qian, Sun, Yan, Fan, Zheng, Qi, Jianxun, Gao, George F., Shi, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: The Author(s). 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260489/
https://ncbi.nlm.nih.gov/pubmed/32531208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107774
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