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Structural Basis of SARS-CoV-2 Polymerase Inhibition by Favipiravir

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has developed into an unprecedented global pandemic. Nucleoside analogs, such as Remdesivir and Favipiravir, can serve as the first-line broad-spectrum antiviral drugs by targeting the viral polymerases. However, the underl...

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Detalhes bibliográficos
Publicado no:Innovation (Camb)
Main Authors: Peng, Qi, Peng, Ruchao, Yuan, Bin, Wang, Min, Zhao, Jingru, Fu, Lifeng, Qi, Jianxun, Shi, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7834001/
https://ncbi.nlm.nih.gov/pubmed/33521757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xinn.2021.100080
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