Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

The H2A.Z histone variant, a genome-wide hallmark of permissive chromatin, is enriched near transcription start sites in all eukaryotes. H2A.Z is deposited by the SWR1 chromatin remodeler and evicted by unclear mechanisms. We tracked H2A.Z in living yeast at single-molecule resolution, and found tha...

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Vydáno v:eLife
Hlavní autoři: Ranjan, Anand, Nguyen, Vu Q, Liu, Sheng, Wisniewski, Jan, Kim, Jee Min, Tang, Xiaona, Mizuguchi, Gaku, Elalaoui, Ejlal, Nickels, Timothy J, Jou, Vivian, English, Brian P, Zheng, Qinsi, Luk, Ed, Lavis, Luke D, Lionnet, Timothee, Wu, Carl
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Chromosomes and Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259955/
https://ncbi.nlm.nih.gov/pubmed/32338606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55667
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