Stepwise histone replacement by SWR1 requires dual activation with histone H2A.Z and canonical nucleosome

Histone variant H2A.Z-containing nucleosomes are incorporated at most eukaryotic promoters. This incorporation is mediated by the conserved SWR1 complex, which replaces histone H2A in canonical nucleosomes with H2A.Z in an ATP-dependent manner. Here, we show that promoter-proximal nucleosomes are hi...

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Udgivet i:Cell
Main Authors: Luk, Ed, Ranjan, Anand, FitzGerald, Peter C., Mizuguchi, Gaku, Huang, Yingzi, Wei, Debbie, Wu, Carl
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251641/
https://ncbi.nlm.nih.gov/pubmed/21111233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.10.019
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