Nucleosome free region dominates histone acetylation in targeting SWR1 to yeast promoters for H2A.Z replacement

The histone variant H2A.Z is a genome-wide signature of nucleosomes proximal to eukaryotic regulatory DNA. While the multi-subunit chromatin remodeler SWR1 is known to catalyze ATP-dependent deposition of H2A.Z, the mechanism of SWR1 recruitment to S. cerevisiae promoters has been unclear. A sensiti...

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Main Authors: Ranjan, Anand, Mizuguchi, Gaku, FitzGerald, Peter C., Wei, Debbie, Wang, Feng, Huang, Yingzi, Luk, Ed, Woodcock, Christopher L, Wu, Carl
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815578/
https://ncbi.nlm.nih.gov/pubmed/24034247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.08.005
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